Postdoctoral Research Fellow (Brugmann) - Developmental and Computational Biology
Cincinnati Children's Hospital Medical Center

Job Description

At Cincinnati Children's, we come to work with one goal: to make children's health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children's.

Cincinnati Children's Hospital Has Been Named:

• Consistently recognized by U.S. News & World Report as a top 10 children's hospital in the nation
• One of four Medical Centers making the list of the 2022 Glassdoor Best Places to Work
• A Top Hospital and Health System for Diversity recognized by DiversityInc
• One of the nation's most innovative companies by Fortune in March 2023
• An LGBTQ+ Healthcare Equality Top Performer in 2022 by The Human Rights Campaign (HRC)

The Brugmann Lab is looking for a postdoctoral fellow interested in combining developmental and computational biology to further our understanding of craniofacial development and disease.

Craniofacial abnormalities (CFAs) are associated with approximately one-third of all birth defects. Patients with a CFA represent a biomedical burden nearly 45 times higher than unaffected children; and in the U.S. alone, the lifetime cost for treating children born with CFAs is approximately $697 million per year. The Brugmann laboratory focuses on understanding the molecular, cellular, and genetic factors that guide craniofacial development. To do so, we have focused on the function of the primary cilium, a ubiquitous, microtubule-based organelle used by all cells to integrate and transduce molecular signals. We aim to elucidate how primary cilia function during facial development and uncover how basic cellular processes are impacted when cilia are impaired. To achieve this goal, we generate and analyze large data sets (RNA-seq, ChIP-seq, CUT&RUN) from animal (murine and avian) and human (iPSC) ciliopathic models.

Relevant publications: eLife 2020 PMID: 33006313

MAJOR DUTIES AND RESPONSIBILITIES:

• Design, execute, and record laboratory experiments, and analyze the data.

• Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department.

• Present research at laboratory meetings, journal clubs, seminars, and meetings.

• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.

• Maintain currency in field through continuing education, literature, and seminars.

• Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all policies and procedures.

• Perform other duties as assigned.

EDUCATION\WORK EXPERIENCE: Ph.D. in related discipline, MD, or equivalent required.

Interested candidates must have a PhD and have a strong record of accomplishments and experience in:

1- Developmental biology, Molecular biology, Craniofacial biology, Ciliary biology; OR

2- Bioinformatics, computational biology.

We are looking for a colleague who is highly motivated and independent.

REQUIRED SKILLS: Excellent written, verbal, and interpersonal communication skills. Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design. Computer literate and working knowledge of software applications (word processing, spreadsheet, and database). Analytical ability sufficient to compare data; mathematical ability sufficient to perform algebraic calculations and statistical analysis. Ability to synthesize information and to create and deal with new situations by applying past experiences. Expressed willingness to teach others and share results. Capable of meeting time demands necessary to execute experiments.

Market Leading Benefits Including*:

• Shift Differential, Weekend Differential, and Weekend Option Pay Programs
• Medical coverage starting day 1 of employment. View employee benefits here.
• Competitive retirement plans
• Tuition reimbursement for continuing education
• Expansive employee discount programs through our many community partners
• Referral bonus program for current staff!
• Support through Employee Resource Groups such as African American Professionals Advisory Council, Asian Cultural and Professional Group, EQUAL - LGBTQIA Resource Group, Juntos - Hispanic/Latin Resource Group, Veterans and Military Family Advocacy Network, and Young Professionals (YP) Resource Group
• Physical and mental health wellness programs
• Relocation assistance available for some positions

*Benefits may vary based on FTE Status and Position Type

Primary Location
Location R

Schedule
Full time

Shift
Day (United States of America)

Department
DB - Brugmann

Employee Status
Regular

FTE
1

Weekly Hours
40

Comprehensive job description provided upon request.

Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/AA/M/F/Veteran/Disability.

---